ID 110806
Author
Kubo, Shin-ichi Department of Forensic Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School
Ishigami, Akiko Department of Forensic Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Gotohda, Takako Department of Forensic Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School
Tokunaga, Itsuo Department of Forensic Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School
Kitamura, Osamu Department of Forensic Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School
Keywords
cause of death
adrenal insufficiency
panhypopituitarism
hypophysectomy
endocrinology
Content Type
Journal Article
Description
A 63-years-oldman was found dead with the body soaking in water lying face up on a riverbank. Autopsy and diatom examination demonstrated that the cause of death was drowning. He had undergone hypophysectomy 20 years earlier. Autopsy, pathological and endocrinological findings demonstrated secondary and chronic hypothyroidism, hypogonadism, and adrenal in sufficiency. The cadaver had fallen into the river, and received numerous wounds such as abrasions and subcutaneous hemorrhage. Moreover, it was suspected that he had developed hypothermia before death. Cortisol in the blood and 17-OHCSin urine were within the reference range. We suspect that the adrenocortical hormone was secreted into the blood as a result of various stresses due to wounds and hypothermia. However, it was suspected that sufficient hormone might not be secreted due to chronic adrenal insufficiency. This insufficient cortisol causes the decrease in the stress resistance, and might influence his cause of death. Moreover, as hypothyroidism decreases thermogenesis, he might have fallen into hypothermia easily. In addition, because both adrenocortical insufficiency and hypothyroidism caused the hypoglycemia, he might have fallen into the loss of consciousness. Therefore, it was considered that he had died by drowning, in relation to the adrenocortical insufficiency and panhypopituitarism.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
53
Issue
1-2
Start Page
183
End Page
187
Sort Key
183
Published Date
2006-02
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences