Dahifar, Hossein Department of Pediatrics, Shaheed Beheshti University of Medical Sciences and Health Services
Faraji, Ali Department of Pediatrics, Shaheed Beheshti University of Medical Sciences and Health Services
Ghorbani, Aboulfazl Department of Pediatrics, Shaheed Beheshti University of Medical Sciences and Health Services
Yassobi, Saeid Department of Pediatrics, Shaheed Beheshti University of Medical Sciences and Health Services
Objective : To study daily intake of calcium, phosphorus and vitamin D,to determine the biochemical findings of rickets and the effect of sunlight exposure and vitamin D supplemention in school girls with hypovitaminosis D. Methods: A cross-sectional study was conducted on school girls aged 11-15 years selected randomly from various areas of Tehran, Iran. Dietary information and amount of sunlight exposure were estimated by a 7 day recalling method using self-reported questionnaire. Hypovitaminosis D defined as low serum 25-hydroxyvitamin D concentration with two or more others abnormal biochemical findings. Girls with hypovitaminoses D were randomly divided into two groups. The faces and hands of girls in group 1were exposed to sunlight for one hour per day for twenty days, while those in group 2 were administered vitamin D capsules, 50,000 IU per day for the same period. Results : four-hundred fourteen girls evaluated, mean daily calcium intake, sunlight exposure and vitamin D acquirement were 360 mg, 10minutes and 119 IU, respectively. Mean serum 25-hydroxyvitamin D concentration was 30 ng/ml among all girls whereas in 15 (3.63%) of 414 girls was 7.8 ng/ml. Abnormal biochemical findings in these girls included hypocalcemia (n=4), hypophosphatemia (n=5), raised serum alkaline phosphatase (n=13), and parathyroid hormone (n=15). After intervention, mean serum 25-hydroxyvitamin D concentration in sunlight exposure (n=8) and vitamin D (n=7) supplementation increased to 14.4±4 ng/ml and 23±4 ng/ml respectively. There was a significant difference between the two groups (plt0.05). Conclusion: Vitamin D deficiency developed in rapid growth period of girls without clear clinical rickets in sunny temperate climate city in Iran which vitamin D supplemention improved biochemical findings better than sunlight exposure.
The journal of medical investigation : JMI
jmi_53_3-4_204.pdf 40.7 KB