ID | 110864 |
Author |
Matsushita, Shingo
Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
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Naito, Takeshi
Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
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Takebayashi, Masaru
Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
Sato, Hiroyuki
Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
Shiota, Hiroshi
Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
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Keywords | PDT
AMD
PCV
subretinal hemorrhage
risk
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Content Type |
Journal Article
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Description | Purpose : To investigate cases with massive subretinal hemorrhage after photodynamic therapy(PDT). Subjects and Methods : We studied four cases(3 men and 1 woman, mean 80.5 yeas old) with massive subretinal hemorrhage after PDT about type of disease, spot size, period to the onset of hemorrhage, visual acuity (VA) before and after PDT. Results : Four cases consisted of one with age-related macula degeneration (AMD) and 3 with polypoidal choroidal vasculopathy (PCV). The average spot size of PDT was 5525_m. Two patients underwent the second PDT about 3 months after the initial PDT. Four periods to the onset of hemorrhage were 22, 27, 137, and 208 days respectively. The latter 2 cases underwent PDT twice, and the periods were the days from the initial PDT. Two patients among four underwent vitrectomy. Average VA before PDT was 0.20, and the final one was 0.02 after PDT. Conclusions : PDT has a risk to cause massive subretinal hemorrhage leading to grave visual disturbance. Especially PDT for PCV seems to have more risk. Therefore we need to inform patients about the risk before PDT, since treating patients with massive subretinal hemorrhage is very difficult.
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Journal Title |
The journal of medical investigation : JMI
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ISSN | 13431420
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NCID | AA11166929
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Volume | 55
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Issue | 3-4
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Start Page | 231
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End Page | 235
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Sort Key | 231
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Published Date | 2008-08
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DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
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departments |
Medical Sciences
International Center
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