ID 110871
Author
Sato, Hiroyuki Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
Naito, Takeshi Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Matsushita, Shingo Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN Search Researchers
Takebayashi, Masaru Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
Shiota, Hiroshi Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
diabetic macular edema
optical coherence tomography
sub-Tenon’s capsule injection
triamcinolone acetonide
vitrectomy
Content Type
Journal Article
Description
To determine whether or not a sub-Tenon’s capsule injection of triamcinolone acetonide(TA) is an effective treatment for refractory diabetic macular edema after vitrectomy. Methods : Thirty-nine eyes of 26 patients with diabetic macular edema were injected with 20 mg TA into the sub-Tenon’s capsule. The central macular thickness (CMT) measured by an optical coherence tomography (OCT) and visual acuities were compared between pre-treatment and 1, 3 months post -treatment. Results : The decrease in the mean CMT between the baseline (435 μm) and 1month (326 μm) or 3months (303 μm) time points was statistically significant. Seven eyes (70%) at 1 month and 3 months post-treatment in the vitrectomized eyes or PPV(pars plana vitrectomy)(+) group, 15 eyes(52%) at 1 month, and 19 eyes (66%) at 3 months in the non-vitrectomized eyes or PPV(-)group maintained 20% reduction in CMT from pre-treatment with a single injection of TA. The recurrence of macular edema was observed in 1 eye (14%) in the PPV(+)group, and 3 eyes (16%) in the PPV(-)group. Conclusion : The sub-Tenon’s capsule injection of TA was effective for refractory diabetic macular edema after vitrectomy. In addition, it was suggested that the treatment of vitrectomized eyes was more effective than that of non-vitrectomized eyes.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
55
Issue
3-4
Start Page
279
End Page
282
Sort Key
279
Published Date
2008-08
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
International Center
Medical Sciences