ID 111155
Title Alternative
UVA照射と抗生物質投与の併用により、腸炎ビブリオに対してより強い殺菌効果を得ることができる
Combined treatment of UVA and antibiotics
Author
Hou, Yanfei Tokushima University
Harada, Yumi Tokushima University
Tsunedomi, Akari Tokushima University
Keywords
UVA
LED
bactericidal effect
synergistic benefit
antibiotics
Content Type
Thesis or Dissertation
Description
The presence of antibiotics in the environment and their subsequent impact on the development of multi-antibiotic resistant bacteria has raised concerns globally. Consequently, much research is focused on a method to produce a better disinfectant. We have established a disinfectant system using UVA-LED that inactivates pathogenic bacteria. We assessed the bactericidal efficiency of a combination of UVA-LED and antibiotics against Vibrio parahaemolyticus. Combined use of antibiotic drugs and UVA irradiation was more bactericidal than UVA irradiation or antibacterial drugs alone. The bactericidal synergy was observed at low concentrations of each drug that are normally unable to kill the bacteria. This combination has the potential to become a sterilization technology.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
AA12022913
Publisher
Faculty of Medicine Tokushima University
Volume
63
Issue
1-2
Start Page
63
End Page
67
Sort Key
63
Published Date
2016-02
Remark
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201603171003.pdf
論文本文 : LID201603171004.pdf
本論文は,著者Yanfei Houの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第2894号
Diploma Number
甲栄第232号
Granted Date
2016-01-28
Degree Name
Doctor of Nutritional Science
Grantor
Tokushima University
departments
Bioscience and Bioindustry
Medical Sciences
Science and Technology