ID | 111307 |
Author |
Nishisako, Hirotaka
Tokushima University
Ikehara, Toshitaka
Tokushima Bunri University
Shiraishi, Tairoh
Tokushima University
Minami, Yuki
Tokushima University
Ichinose(Sasaki), Hiromi
Kagawa University
Houchi, Hitoshi
Kagawa University
Minakuchi, Kazuo
Tokushima University
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Yoshizaki, Kazuo
The University of Tokushima
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Kinouchi, Yohsuke
The University of Tokushima
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Miyamoto, Hiroshi
The University of Tokushima
|
Keywords | eddy current
cytoskeletal protein
actin
hyposmotic stress
regulatory volume decrease
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Content Type |
Journal Article
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Description | Effects of a time-varying magnetic field on cell volume regulation by hyposmotic stress in cultured bovine adrenal chromaffin cells were examined. Through regulatory volume decrease (RVD), cell volume of chromaffin cells that were incubated in a hypotonic medium initially increased, reached a peak and finally recovered to the initial value. Two hour exposure to a magnetic field and addition of cytochalasin D increased peak value and delayed return to initial value. Intracellular F-actin contents initially decreased but returned to normal levels after 10 sec. Two hour exposure to the magnetic field and addition of cytochalasin D continuously reduced the F-actin content. Results suggest that exposure to the magnetic field stimulated disruption of the actin cytoskeleton and that the disruption delayed the recovery to the volume prior to osmotic stress.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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NCID | AA11166929
AA12022913
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Publisher | Faculty of Medicine Tokushima University
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Volume | 58
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Issue | 1-2
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Start Page | 95
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End Page | 105
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Sort Key | 95
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Published Date | 2011-02
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
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departments |
Pharmaceutical Sciences
Medical Sciences
Technical Support Department
Science and Technology
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