ID 111307
Author
Nishisako, Hirotaka Tokushima University
Ikehara, Toshitaka Tokushima Bunri University
Shiraishi, Tairoh Tokushima University
Minami, Yuki Tokushima University
Ichinose(Sasaki), Hiromi Kagawa University
Houchi, Hitoshi Kagawa University
Shono, Masayuki The University of Tokushima KAKEN Search Researchers
Miyamoto, Hiroshi The University of Tokushima
Keywords
eddy current
cytoskeletal protein
actin
hyposmotic stress
regulatory volume decrease
Content Type
Journal Article
Description
Effects of a time-varying magnetic field on cell volume regulation by hyposmotic stress in cultured bovine adrenal chromaffin cells were examined. Through regulatory volume decrease (RVD), cell volume of chromaffin cells that were incubated in a hypotonic medium initially increased, reached a peak and finally recovered to the initial value. Two hour exposure to a magnetic field and addition of cytochalasin D increased peak value and delayed return to initial value. Intracellular F-actin contents initially decreased but returned to normal levels after 10 sec. Two hour exposure to the magnetic field and addition of cytochalasin D continuously reduced the F-actin content. Results suggest that exposure to the magnetic field stimulated disruption of the actin cytoskeleton and that the disruption delayed the recovery to the volume prior to osmotic stress.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
AA12022913
Publisher
Faculty of Medicine Tokushima University
Volume
58
Issue
1-2
Start Page
95
End Page
105
Sort Key
95
Published Date
2011-02
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Pharmaceutical Sciences
Medical Sciences
Technical Support Department
Science and Technology