ID 111309
Author
Katsenos, Stamatis Army General Hospital of Athens|University Hospital of Ioannina
Nikolopoulou, Melita Army General Hospital of Athens
Rallis, Efstathios Army General Hospital of Athens
Constantopoulos, Stavros H University Hospital of Ioannina
Keywords
bronchoalveolar lavage
chronic eosinophilic pneumonia
neurofibromatosis-1
peripheral eosinophilia
Content Type
Journal Article
Description
Neurofibromatosis type 1 (formerly known as von Recklinghausen’s disease) is an autosomal dominant disorder, which results from the proliferation of the neural crest cells, thus affecting any organ system. Several pulmonary manifestations have hitherto been reported, including chest wall deformities, diffuse lung disease, thoracic neoplasms, pulmonary arterial hypertension, central hypoventilation, diaphragmatic paralysis and meningocele. However, eosinophilic lung disorders have not been described. An unusual case of chronic eosinophilic pneumonia in a patient with neurofibromatosis type 1, is reported herein. He had a propitious outcome, following corticosteroid treatment. This is the first well-documented case of chronic eosinophilic pneumonia and neurofibromatosis type 1 in the same patient. These clinical entities might share common pathogenic mechanisms, as suggested by the present study, that could explain their co-existence.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
AA12022913
Publisher
Faculty of Medicine Tokushima University
Volume
56
Issue
1-2
Start Page
64
End Page
69
Sort Key
64
Published Date
2009-02
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher