Oshio, Atsuo The University of Tokushima
Tamaki, Katsuyoshi The University of Tokushima
Shimizu, Ichiro The University of Tokushima
Fukuno, Hiroshi The University of Tokushima
Urata, Mari The University of Tokushima
Ito, Susumu The University of Tokushima Tokushima University Educator and Researcher Directory
Sano, Nobuya Tokushima University
Objective : We compared the duration of ablation and the area of coagulation necrosis between a single ablation method (SAM) and a double ablation method (DAM) with a ’multitined expandable’ electrode (LeVeen 2cm) for radiofrequency ablation (RFA) using pig liver.
Method : In the SAM group, ablation was completed after the first roll-off. In the DAM group, an additional ablation was performed to achieve a second roll-off. The comparison was made of the time required for roll-off and the extent of coagulation necrosis between the both groups. The Ellipticity index (EI) quantitatively describes the shape of the general RF ablation zone in the axial plane.
Results : There was no statistically significant difference in the interval until the first roll-off between both groups (SAM group : 100.7±24.7 seconds vs DAM group : 103.2±37.7 seconds, P=0.43). In the DAM group, the interval from the start of the additional ablation until the second roll-off was 154.0±86.9 seconds, longer than the interval for the first roll-off (P=0.023). The extent of coagulation necrosis was significantly more extensive in the DAM group (axial diameter, mean±SD, 26.2±2.8 mm)×(maximal diameter : 29.3±1.6 mm)× (minimal diameter : 26.5±3.6 mm) compared to the SAM group with (23.0±3.3 mm)×(23.7± 3.1 mm)×(20.0±2.5 mm), respectively. Although there was no statistically significant difference in the EI between both groups, macroscopically, the shape of coagulation necrosis tended to be non-spherical in the SAM group and spherical in the DAM group. Conclusions : The DAM with a ’multitined expandable’ electrode was more extensive with a spherical zone shape compared to the SAM.
The Journal of Medical Investigation
Faculty of Medicine Tokushima University
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