Sex differences in Auditory Evoked Potential (AEP) and EEG of healthy adults
Nakayama, Hiroshi The University of Tokushima
Kaneda, Yasuhiro The University of Tokushima
Kagawa, Kouichi The University of Tokushima
Nagamine, Isao The University of Tokushima
Karisya, Kenji The University of Tokushima
Furuta, Noriko The University of Tokushima
Ikuta, Takumi The University of Tokushima
Sex differences in AEP (Auditory Evoked Potential) and EEG were studied with 100 healthy adult males (mean age=25.4± 3.1 y. o.) and 100 adult females (mean age=21.6± 2.6 y. o.). AEPs evoked by binaural clicks were recorded with 1024 msec of analysis time through the two derivations (3CH : Cz→A1+2 and 6CH : Cz→T5).
The differences between the two group mean AEPs of each sex were studied. The differences in latencies and peak-to-peak amplitudes of individual AEPs between sexes were tested statistically. The following results were obtained.
1 The waveform of group mean AEPs of each sex had hexaphasic contour, consisted of components P1~N8, including the prominent negative peak N4 and positive peak P5, within 600 msec of latency.
2 The contours of group mean AEP were similar in both sexes, but the latencies of the components were shorter, and peak-to-peak amplitudes were larger in females than in males.
3 Most of latencies and peak-to-peak amplitudes were significantly shorter in females than in males by t-test.
4 The significant sex differences of latencies and amplitudes of AEP components, including the most prominent component P5, were verified even after excluding the influence of stature and body weight, by analysis of covariance.
5 Quantitative analysis of EEG between sexes resulted in larger band amplitude in males and significantly larger θ and β1 power % and smaller α2 power % in females.
The sex differences in AEP verified in this study were attributed to the less differentiated lateralities of the brain in females, than in males.
Shikoku Acta Medica
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