ID 111874
Author
Hayashi, Tsukiho Tokushima University
Osawa, Ayumi Hokkaido University
Watanabe, Takehiro Suntory Foundation of Life Sciences
Murata, Yoshiko Suntory Foundation of Life Sciences
Keywords
iron ion sensor
fluorescence quenching
1,3a,6a-triazapentalene
enterobactin
siderophore
Content Type
Journal Article
Description
1,3a,6a-Triazapentalene (TAP)-labeled enterobactin was developed as an iron ion sensor. 3-Acetylated-TAP was successfully introduced to the catechol ring of enterobactin, a well-recognized siderophore secreted by various Gram-negative bacteria. The fluorescence of TAPlabeled enterobactin decreased gradually as the amount of Fe3+ ion as an additive was increased, and 1.2 equiv of Fe3+ ion completely quenched the fluorescence. In clear contrast, when other metal ions were used, the fluorescence of TAP-labeled enterobactin remained even at 5.0 equiv.
Journal Title
Tetrahedron Letters
ISSN
00404039
NCID
AA00861801
AA11539822
Publisher
Elsevier
Volume
58
Issue
20
Start Page
1961
End Page
1964
Published Date
2017-04-05
Rights
© 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Author
departments
Pharmaceutical Sciences