ID 112237
Title Alternative
Anthropometrics estimates renal function
Author
Otani, Tomoko Tokushima University|Naruto Yamakami Hospital
Kase, Yasuko Naruto Yamakami Hospital
Kunitomo, Kazufumi Naruto Yamakami Hospital
Shimooka, Kazumi
Naoe, Mitsugu Naruto Yamakami Hospital
Yamamoto, Hiroko Naruto Yamakami Hospital
Keywords
creatinine clearance
estimation of renal function
bedridden elderly patients
triceps skinfold thickness
“Naruto” formula
Content Type
Journal Article
Description
In recumbent elderly patients, creatinine clearance (eCCr) estimated by the Cockcroft-Gault (CG) equation may not necessarily reflect renal function. We aimed to develop a novel formula to revise the CG equation using anthropometric measurements in bedridden elderly patients and evaluate its clinical utility. The subjects included 77 bedridden Japanese patients aged ≥ 65, hospitalized at Naruto Yamakami Hospital. The actual CCr (mCCr) value was measured using the 24-hour urine collection method. Anthropometric data, such as skeletal muscle mass, body fat mass (BFM), and triceps skinfold thickness (TSF), were collected. We established a novel formula to estimate CCr(BFM) or CCr(TSF) by correcting the eCCr(Enz + 0.2) value with BFM or TSF. The stage of classification of renal dysfunctions in patients with eGFR(BFM) or eGFR(TSF) was equivalent to the GFR(control) based on the mCCr. Notably, the novel equation for eCCr based on TSF (eCCr(TSF)), dubbed the “Naruto” formula, can be useful to evaluate renal function in bedridden elderly patients without expensive equipment or additional costs. In this study, mCCr was considered to be the true renal function of the patient, but whether and to what extent mCCr correlates with inulin clearance is unknown.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA12022913
AA11166929
Publisher
Faculty of Medicine Tokushima University
Volume
65
Issue
3-4
Start Page
195
End Page
202
Sort Key
195
Published Date
2018-08
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Pharmaceutical Sciences