ID 112968
Author
Asada, Yoshimasa Asada Ladies Clinic Medical Corporation
Morimoto, Yoshiharu HORAC Grand Front Osaka Clinic
Nakaoka, Yoshiharu IVF Namba Clinic
Yamasaki, Takahiro Yamaguchi University
Suehiro, Yutaka Yamaguchi University
Sugimoto, Hikaru Roche Diagnostics
Yoshida, Masayuki Roche Diagnostics
Keywords
anti-Müllerian hormone
Japanese
oocyte retrieval
ovarian reserve
ovulation induction
Content Type
Journal Article
Description
Purpose: To compare the ovarian response predictive ability of anti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH), and estradiol (E2) and to determine the age-specific distribution of serum AMH concentrations of Japanese women.
Methods: This was a multicenter (four-site), observational, analytic, cross-sectional Japanese study consisting of two parts: Study 1 (the prediction of the ovarian response of 236 participants who were undergoing controlled ovarian stimulation [COS]) and Study 2 (the distribution of the AMH concentration with an assay of 417 healthy women who were aged 20-49 years and who had normal menstrual cycles).
Results: The AMH had a significantly higher predictive value for the normal and high responders than FSH and E2 as a stronger correlation between the ovarian response and AMH was observed than for FSH and E2. The serum AMH concentration decreased proportionally with age.
Conclusion: The AMH concentration correlated well with the oocyte count in the patients who were undergoing COS for in vitro fertilization and was shown to predict the risk of ovarian hyperstimulation syndrome among these patients.
Journal Title
Reproductive Medicine and Biology
ISSN
14470578
NCID
AA11706516
Publisher
Japan Society for Reproductive Medicine|John Wiley & Sons Australia, Ltd
Volume
16
Issue
4
Start Page
364
End Page
373
Published Date
2017-09-18
Rights
© 2017 The Authors. Reproductive Medicine and Biology published by John Wiley & Sons Australia, Ltd on behalf of Japan Society for Reproductive Medicine. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
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DOI (Published Version)
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language
eng
TextVersion
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departments
Medical Sciences