ID 113021
Author
Enomoto, Yuuki Tokushima University
Uryu, Mizuho Tokushima University|Hokkaido University
Yang, Xicheng Hokkaido University
Kataoka, Ayami Tokushima University
Ohnishi, Atsushi Daicel Corporation
Content Type
Journal Article
Description
A series of polysaccharide-based chiral stationary phase (CSP) columns, Daicel Chiralpak IA, IB, and IC, were applied in the separation of the nonenantiomeric isomers of various organometallic compounds and were found to be highly effective in recognizing isomers of minor structural differences. The CSP columns have succeeded to separate the double-bond regioisomers in bridged (η5-formylcyclopentadienyl)manganese(I) dicarbonyl complexes 1a/1b, the structural isomers of methylbutenylferrocene derivatives in 2a/2b and 3a/3b, and the geometrical isomers of the (2-methyl-2-butenyl)ferrocenes in (Z)/(E)-3b. Due to the close similarity of the isomeric compounds in these mixtures, separations of the components are extremely difficult and could not be attained by conventional methods such as silica gel column chromatography, silica gel HPLC, recrystallization, distillation/sublimation, etc. Clearly, the polysaccharide-based CSP columns have unique advantages in separation/purification technology, and this study has shown potential usefulness of the CSP columns in separation of not only enantiomeric but also nonenantiomeric mixtures.
Journal Title
Organometallics
ISSN
02767333
15206041
NCID
AA10627775
AA12097286
Publisher
ACS Publications
Volume
38
Issue
2
Start Page
512
End Page
518
Published Date
2018-12-20
Rights
This is an open access article published under an ACS AuthorChoice License(https://pubs.acs.org/page/policy/authorchoice_termsofuse.html), which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Science and Technology