number of access : ?
number of downloads : ?
ID 113405
Title Alternative
CRP in PMR and RS3PE syndrome
Author
Tabata, Ryo The University of Tokushima KAKEN Search Researchers
Yuasa, Shino Tokushima Prefectural Central Hospital
Nakanishi, Yoshinori The University of Tokushima
Kawahito, Keisuke Yoshinogawa Medical Center
Inaba, Keisuke The University of Tokushima
Inaba, Kaori The University of Tokushima
Umetani, Kazumasa Tokyo Bei Urayasu Ichikawa Medical Center
Miyatake, Akiko Naruto Yamakami Hospital
Keywords
PMR
RS3PE syndrome
C-reactive protein
prednisolone
relapse
Content Type
Journal Article
Description
Polymyalgia rheumatica (PMR) and remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome are common inflammatory rheumatic diseases in the elderly. In this study, we investigate predictive factors which correspond to subsequent disease control of PMR and RS3PE syndrome. Twenty four patients, which contained 18 PMR and 6 RS3PE syndrome, were treated with initial dosages of 10-20 mg per day oral prednisolone, and the dosage of prednisolone was then tapered. Significantly higher initial CRP was observed in patients with poor disease control than in those with good disease control afterwards. The number of patients with negative CRP after 4 weeks was significantly more in patients with good disease control after 1 year than in those with poor disease control. Patients were shown to be in good disease control status after 1 year when CRP after 4 weeks became negative even if they had initial high CRP. Our study clarify that to make CRP negative after 4 weeks is associated with subsequent suppression of the disease activity and with decreased dosages of corticosteroids.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA12022913
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
66
Issue
1-2
Start Page
112
End Page
118
Sort Key
112
Published Date
2019-02
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
University Hospital
Medical Sciences