ID | 114105 |
Title Alternative | Two-stage sinus floor augmentation using carbonate apatite
|
Author |
Kudoh, Keiko
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Fukuda, Naoyuki
Tokushima University
Tokushima University Educator and Researcher Directory
KAKEN Search Researchers
Kasugai, Shohei
Tokyo Medical and Dental University
Tachikawa, Noriko
Tokyo Medical and Dental University
Koyano, Kiyoshi
Kyushu University
Matsushita, Yasuyuki
Kyushu University
Sasaki, Masanori
Kyushu University
Ishikawa, Kunio
Kyushu University
|
Keywords | Apatites
Dental implant
Sinus floor augmentation
|
Content Type |
Journal Article
|
Description | Purpose: The purpose of this study was to elucidate the efficacy and safety of carbonate apatite (CO3Ap) granules in 2-stage sinus floor augmentation through the radiographic and histomorphometric assessment of bone biopsy specimens.
Methods: Two-stage sinus floor augmentation was performed on 13 patients with a total of 17 implants. Radiographic assessment using panoramic radiographs was performed immediately after augmentation and was also performed 2 additional times, at 7±2 months and 18±2 months post-augmentation, respectively. Bone biopsy specimens taken from planned implant placement sites underwent micro-computed tomography, after which histological sections were prepared. Results: Postoperative healing of the sinus floor augmentation was uneventful in all cases. The mean preoperative residual bone height was 3.5±1.3 mm, and this was increased to 13.3±1.7 mm by augmentation with the CO3Ap granules. The mean height of the augmented site had decreased to 10.7±1.9 mm by 7±2 months after augmentation; however, implants with lengths in the range of 6.5 to 11.5 mm could still be placed. The mean height of the augmented site had decreased to 9.6±1.4 mm by 18±2 months post-augmentation. No implant failure or complications were observed. Few inflammatory cells or foreign body giant cells were observed in the bone biopsy specimens. Although there were individual differences in the amount of new bone detected, new bone was observed to be in direct contact with the CO3Ap granules in all cases, without an intermediate layer of fibrous tissue. The amounts of bone and residual CO3Ap were 33.8%±15.1% and 15.3%±11.9%, respectively. Conclusions: In this first demonstration, low-crystalline CO3Ap granules showed excellent biocompatibility, and bone biopsy showed them to be replaced with bone in humans. CO3Ap granules are a useful and safe bone substitute for two-stage sinus floor augmentation. |
Journal Title |
Journal of Periodontal & Implant Science
|
ISSN | 20932278
20932286
|
Publisher | Korean Academy of Periodontology
|
Volume | 49
|
Issue | 6
|
Start Page | 382
|
End Page | 396
|
Published Date | 2019-10-09
|
Rights | © 2019. Korean Academy of Periodontology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/). |
EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
|
TextVersion |
Publisher
|
departments |
Oral Sciences
|