Total for the last 12 months
number of access : ?
number of downloads : ?
ID 114949
Koyama, Toshihiro Okayama University
Sasaki, Misato Okayama University
Hagiya, Hideharu Okayama University
Funahashi, Tomoko Okayama University
Ohshima, Ayako Okayama University
Tatebe, Yasuhisa Okayama University
Mikami, Naoko Chiba University
Shinomiya, Kazuaki Tokushima Bunri University
Kitamura, Yoshihisa Okayama University
Sendo, Toshiaki Okayama University
Hinotsu, Shiro Sapporo Medical University
Kano, Mitsunobu R. Okayama University|University of Tokyo
Content Type
Journal Article
Dementia is a major public health concern in ageing societies. Although the population of Japan is among the most aged worldwide, long-term trends in the place of death (PoD) among patients with dementia is unknown. In this Japanese nationwide observational study, we analysed trends in PoD using the data of patients with dementia who were aged ≥65 years and died during 1999–2016. Trends in the crude death rates and PoD frequencies were analysed using the Joinpoint regression model. Changes in these trends were assessed using the Joinpoint regression analysis in which significant change points, the annual percentage change (APC) and average APCs (AAPC) in hospitals, homes, or nursing homes were estimated. During 1999–2016, the number of deaths among patients with dementia increased from 3,235 to 23,757 (total: 182,000). A trend analysis revealed increased mortality rates, with an AAPC of 8.2% among men and 9.3% among women. Most patients with dementia died in the hospital, although the prevalence of hospital deaths decreased (AAPC: -1.0%). Moreover, the prevalence of nursing home deaths increased (AAPC: 5.6%), whereas the prevalence of home deaths decreased (AAPC: -5.8%). These findings support a reconsideration of the end-of-life care provided to patients with dementia.
Journal Title
Scientific Reports
Springer Nature
Start Page
Published Date
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit
DOI (Published Version)
URL ( Publisher's Version )
FullText File
Medical Sciences