Murakami, Masahiro Hyogo University of Health Sciences
Katsuragi, Satoko Hyogo University of Health Sciences
Ohno, Masako Hyogo University of Health Sciences
Shigematsu, Makoto Tanimukai Hospital
Kishi, Ayumi Hyogo University of Health Sciences
Zamami, Yoshito Tokushima University KAKEN Search Researchers
Komada, Fusao Himeji Dokkyo University
Kurata, Naomi Showa University
Amano, Manabu Hyogo University of Health Sciences
Oral anticancer drugs
Simple suspension method
Drug-administering persons’ exposure
Objective: The objective of this study was to quantitatively evaluate anticancer drug exposure of non-health care professionals who administer drugs through a tube employing a method devised by us.
Methods: The subjects were 30 general volunteers aged 22-84 years. They wore gloves and administered Indian ink, simulating an anticancer drug, to a multipurpose adult human-type patient care simulator through a tube using 5 types of syringe, and the area stained with Indian ink was measured.
Results: When comparing the number of pixels among the syringes regardless of age, Syringe B showed the lowest number (11.8±3.1 cm2), and there was a significant difference between Syringes B and E. Furthermore, we compared the total number of pixels in each age group regardless of the type of syringe. In the 20-year-old group, it was the lowest (10.9±2.3 cm2) showing significant differences in comparison with the other groups. When Syringe B was used, the number of pixels was markedly lower than on adopting the other syringes.
Conclusion: It was clarified that the level of exposure to anticancer drugs markedly varies depending on the type of syringe and age. It was also clarified that the method to evaluate exposure to anticancer drugs using Indian ink devised by us is simple and useful.
Asian Journal of Pharmaceutical and Clinical Research
Innovare Academic Sciences
© 2016 The Authors. Published by Innovare Academic Sciences Pvt Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/) DOI: http://dx.doi.org/10.22159/ajpcr.2016.v9s3.13040
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