| ID | 115070 |
| Author |
Tsutsumi, Tomohiro
Tokushima University
Saitoh, Arisa
Tokushima University
Kasai, Tomoyo
Tokushima University
Chu, MengYue
Tokushima University
Nakayama, Atsushi
Tokushima University
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Namba, Kosuke
Tokushima University
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|
| Keywords | N,N-Dimethylaminopyridine
1,1,7,7-Tetramethyl-9-azajulolidine
Acylation catalyst
Quinolizidine alkaloid
Cascade reaction
|
| Content Type |
Journal Article
|
| Description | 1,1,7,7-Tetramethyl-9-azajulolidine (TMAJ), which theoretical studies have suggested as a highly active DMAP analog, was synthesized for the first time. The catalytic activity of TMAJ was confirmed by the acetylation reactions of various tert-alcohols. TMAJ showed much higher catalytic activity than DMAP and one of the highest activity levels among the conventional DMAP analogs. These experimental results were in good agreement with the previous theoretical studies.
|
| Journal Title |
Tetrahedron Letters
|
| ISSN | 00404039
|
| NCID | AA00861801
AA11539822
|
| Publisher | Elsevier
|
| Volume | 61
|
| Issue | 26
|
| Start Page | 152047
|
| Published Date | 2020-05-17
|
| Rights | © 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
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| EDB ID | |
| DOI (Published Version) | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
|
| TextVersion |
Author
|
| departments |
Pharmaceutical Sciences
|
