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ID 115538
Title Alternative
CT-based CTVHR for cervical brachytherapy
Author
Ohno, Tatsuya Gunma University
Wakatsuki, Masaru Jichi Medical University
Toita, Takafumi University of the Ryukyus
Kaneyasu, Yuko National Hospital Organization Fukuyama Medical Center
Yoshida, Ken Osaka Medical College
Kato, Shingo Saitama Medical University
Ii, Noriko Mie University
Tokumaru, Sunao Saga University
Uno, Takashi Chiba University
Noda, Shin-ei Gunma University
Kazumoto, Tomoko Fukaya Red Cross Hospital
Harima, Yoko Kansai Medical University
Keywords
cervical cancer
brachytherapy
high-risk clinical target volume
three-dimensional planning
recommendations
Content Type
Journal Article
Description
Our purpose was to develop recommendations for contouring the computed tomography (CT)-based high-risk clinical target volume (CTVHR) for 3D image-guided brachytherapy (3D-IGBT) for cervical cancer. A 15-member Japanese Radiation Oncology Study Group (JROSG) committee with expertise in gynecological radiation oncology initiated guideline development for CT-based CTVHR (based on a comprehensive literature review as well as clinical experience) in July 2014. Extensive discussions occurred during four face-to-face meetings and frequent email communication until a consensus was reached. The CT-based CTVHR boundaries were defined by each anatomical plane (cranial–caudal, lateral, or anterior–posterior) with or without tumor progression beyond the uterine cervix at diagnosis. Since the availability of magnetic resonance imaging (MRI) with applicator insertion for 3D planning is currently limited, T2-weighted MRI obtained at diagnosis and just before brachytherapy without applicator insertion was used as a reference for accurately estimating the tumor size and topography. Furthermore, utilizing information from clinical examinations performed both at diagnosis and brachytherapy is strongly recommended. In conclusion, these recommendations will serve as a brachytherapy protocol to be used at institutions with limited availability of MRI for 3D treatment planning.
Journal Title
Journal of Radiation Research
ISSN
13499157
NCID
AA00705792
Publisher
Oxford University Press|The Japanese Radiation Research Society|Japanese Society for Radiation Oncology
Volume
58
Issue
3
Start Page
341
End Page
350
Published Date
2016-11-10
Rights
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
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DOI (Published Version)
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language
eng
TextVersion
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departments
Medical Sciences