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ID 115830
Author
Yoneyama, Tatsuro Tokushima Bunri University
Iseki, Kanako Tokushima Bunri University
Noji, Masaaki Tokushima Bunri University
Imagawa, Hiroshi Tokushima Bunri University
Hashimoto, Toshihiro Tokushima Bunri University
Kawano, Sachiko Kawano-Mericlone
Baba, Masaki Meiji Pharmaceutical University
Yahagi, Tadahiro Nihon University
Matsuzaki, Keiichi Nihon University
Umeyama, Akemi Tokushima Bunri University
Keywords
Cymbidium Great Flower ‘Marylaurencin’
Orchidaceae
maryloside
nitric oxide production
norcycloartane glycoside
Content Type
Journal Article
Description
Seven novel norcycloartane glycosides, maryloside A–G (1–7), were isolated from the leaves of Cymbidium Great Flower ‘Marylaurencin’, along with a known norcycloartane glycoside, cymbidoside (8). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation and X-ray crystallographic analysis. The isolated compounds (1–6 and 8) were evaluated for the inhibitory activity on lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated nitric oxide (NO) production in RAW 264.7 cells. Consequently, 1 and 3 exhibited moderate activity.
Journal Title
Molecules
ISSN
14203049
Publisher
MDPI
Volume
24
Issue
13
Start Page
2504
Published Date
2019-07-09
Rights
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Pharmaceutical Sciences