ID | 116011 |
Title Alternative | A reduced brain and liver FDG uptake
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Author |
Otomi, Yoichi
Tokushima University
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Otsuka, Hideki
Tokushima University
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Shono, Nahomi
Tokushima University
Onishi, Hajime
Tsurugi Municipal Handa Hospital
Mitsuhashi, Ryota
Tokushima University
Matsuzaki, Saya
Tokushima University
Enomoto, Hideaki
Tokushima University
Sakamoto, Yuko
Tokushima University
Sasahara, Mihoko
Tokushima University
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Keywords | brain
liver
malignant lymphoma
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Content Type |
Journal Article
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Description | Purpose : To investigate whether or not the physiological brain and liver FDG uptake are decreased in patients with highly accelerated glycolysis lesions. Methods : We retrospectively analyzed 51 patients with malignant lymphoma. We compared the FDG uptake in the brain and liver of the patients with that in a control group. In 24 patients with a complete response (CR) or partial response (PR) to treatment, we compared the brain and liver uptake before and after treatment. Results : The maximum standardized uptake value (SUVmax) and total glycolytic volume (TGV) of the brain as well as the SUVmax and mean standardized uptake value (SUVmean) of the liver in malignant lymphoma patients were 13.1 ± 2.3, 7386.3 ± 1918.4, 3.2 ± 0.5, and 2.3 ± 0.4, respectively ; in the control group, these values were 14.9 ± 2.4, 8566.2 ± 1659.5, 3.4 ± 0.4, and 2.5 ± 0.3, respectively. The SUVmax and TGV of the brain and the SUVmean of the liver in malignant lymphoma patients were significantly lower than the control group. The SUVmax and TGV of the brain after treatment were significantly higher than before treatment. Both the SUVmax and SUVmean of liver after treatment were higher than before treatment, but not significant. Conclusion : A decreased physiological brain and liver FDG uptake is caused by highly accelerated lesion glycolysis.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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NCID | AA11166929
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Publisher | Tokushima University Faculty of Medicine
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Volume | 68
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Issue | 1-2
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Start Page | 181
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End Page | 185
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Sort Key | 181
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Published Date | 2021-02
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EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
Publisher
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departments |
University Hospital
Medical Sciences
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