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ID 116481
Title Alternative
Androgen’s effects in female
Author
Shinya, Akari Tokushima University
Minato, Saki Tokushima University
Yanagihara, Rie Tokushima University
Imaizumi, Junki Tokushima University
Nakagawa, Tomotaka Tokushima University
Taniguchi, Miyu Tokushima University
Kadota, Yuri Tokushima University
Keywords
androgen
metabolic function
obesity
Content Type
Journal Article
Description
The metabolic effects of androgens and their underlying mechanisms in females have been revealed by recent studies. An excess of androgens can have adverse effects on feeding behavior and metabolic functions and induce metabolic disorders / diseases, such as obesity, insulin resistance, and diabetes, in women and experimental animals of reproductive age. Interestingly, these effects of androgens are not observed in ovariectomized animals, indicating that their effects might be dependent on the estrogen milieu. Central and peripheral mechanisms, such as alterations in the activity of hypothalamic factors, reductions in energy expenditure, skeletal muscle insulin resistance, and β-cell dysfunction, might be related to these androgens’ effects.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
68
Issue
3-4
Start Page
228
End Page
231
Sort Key
228
Published Date
2021-08
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
University Hospital
Medical Sciences