Total for the last 12 months
number of access : ?
number of downloads : ?
ID 118711
Author
Murata, Takashi National Hospital Organization Kyoto Medical Center
Hosoda, Kiminori National Cerebral and Cardiovascular Center
Nishimura, Kunihiro National Cerebral and Cardiovascular Center
Miyamoto, Yoshihiro National Cerebral and Cardiovascular Center
Sakane, Naoki National Hospital Organization Kyoto Medical Center
Satoh-Asahara, Noriko National Hospital Organization Kyoto Medical Center
Toyoda, Masao Tokai University
Hirota, Yushi Kobe University
Kato, Ken National Hospital Organization Osaka National Hospital
Kouyama, Ryuji Tsuchiura Kyodo General Hospital
Miura, Junnosuke Tokyo Women’s Medical University
Tone, Atsuhito Okayama Saiseikai General Hospital
Kasahara, Masato Nara Medical University
Kasama, Shu Nara Medical University
Suzuki, Shota Nara Medical University
Ito, Yukie Nara Medical University
Watanabe, Tomokazu National Hospital Organization Kyoto Medical Center
Suganuma, Akiko National Hospital Organization Kyoto Medical Center
Shen, Zhuo Tokyo Women’s Medical University
Kobayashi, Hiroko Tokyo Women’s Medical University
Takagi, Satoshi Tokyo Women’s Medical University
Hoshina, Sari Tokyo Women’s Medical University
Shimura, Kanako Tokyo Women’s Medical University
Tsuchida, Yukiko Tokyo Women’s Medical University
Kimura, Moritsugu Tokai University
Saito, Nobumichi Tokai University
Shimada, Akira Saitama Medical University
Oikawa, Yoichi Saitama Medical University
Satomura, Atsushi Saitama Medical University
Haisa, Akifumi Saitama Medical University
Kawashima, Satoshi Kanda Naika Clinic
Meguro, Shu Keio University
Itoh, Hiroshi Keio University
Saisho, Yoshifumi Keio University
Irie, Junichiro Keio University
Tanaka, Masami Keio University
Mitsuishi, Masanori Keio University
Nakajima, Yuya Keio University
Inaishi, Jun Keio University
Kinouchi, Kenichiro Keio University
Yamaguchi, Shintaro Keio University
Itoh, Arata Keio University
Sugiyama, Kazutoshi Keio University
Yagi, Kazuma Keio University
Tsuchiya, Tami Keio University
Kodani, Noriko Keio University
Shimizu, Ikki Sakakibara Heart Institute of Okayama
Fukuda, Tetsuya Sakakibara Heart Institute of Okayama
Kusunoki, Yoshiki Hyogo College of Medicine
Katsuno, Tomoyuki Hyogo College of Medicine
Matoba, Yuka National Hospital Organization Kokura Medical Center
Hitaka, Yumi National Hospital Organization Kokura Medical Center
Abe, Kentaro National Hospital Organization Kokura Medical Center
Tanaka, Natsuko National Hospital Organization Kokura Medical Center
Taniguchi, Ryoko National Hospital Organization Kokura Medical Center
Nagao, Toshihiko National Hospital Organization Kokura Medical Center
Hida, Kazuyuki National Hospital Organization Okayama Medical Center
Iseda, Izumi National Hospital Organization Okayama Medical Center
Takeda, Masaya National Hospital Organization Okayama Medical Center
Matsushita, Yuichi National Hospital Organization Okayama Medical Center
Tenta, Masafumi National Hospital Organization Okayama Medical Center
Tanaka, Tsuyoshi National Hospital Organization Mie Chuo Medical Center
Kouyama, Kunichi National Hospital Organization Hyogo-Chuo National Hospital
Fukunaga, Michiru National Hospital Organization Hyogo-Chuo National Hospital
Keywords
Time below range
Intermittent-scanning continuous glucose monitoring
Education
Randomized trial
Content Type
Journal Article
Description
Aims: We conducted a randomized, crossover trial to compare intermittent-scanning continuous glucose monitoring (isCGM) device with structured education (Intervention) to self-monitoring of blood glucose (SMBG) (Control) in the reduction of time below range.
Methods: This crossover trial involved 104 adults with type 1 diabetes mellitus (T1DM) using multiple daily injections. Participants were randomly allocated to either sequence Intervention/Control or sequence Control/Intervention. During the Intervention period which lasted 84 days, participants used the first-generation FreeStyle Libre (Abbott Diabetes Care, Alameda, CA, USA) and received structured education on how to prevent hypoglycemia based on the trend arrow and by frequent sensor scanning (≥10 times a day). Confirmatory SMBG was conducted before dosing insulin. The Control period lasted 84 days. The primary endpoint was the decrease in the time below range (TBR; <70 mg/dL).
Results: The time below range was significantly reduced in the Intervention arm compared to the Control arm (2.42 ± 1.68 h/day [10.1 %±7.0 %] vs 3.10 ± 2.28 h/day [12.9 %±9.5 %], P = 0.012). The ratio of high-risk participants with low blood glucose index >5 was significantly reduced (8.6 % vs 23.7 %, P < 0.001).
Conclusions: The use of isCGM combined with structured education significantly reduced the time below range in patients with T1DM.
Journal Title
Diabetes Research and Clinical Practice
ISSN
01688227
18728227
NCID
AA1152533X
AA1044374X
Publisher
Elsevier
Volume
195
Start Page
110147
Published Date
2022-11-14
Rights
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Institute of Advanced Medical Sciences