ダイチョウ ガン ニ タイスル 5 FU アイソボリン リョウホウ デ コウカ ガ ミトメラレタ 2レイ
Two cases of colon cancer treated with 5-FU and isovorin
Miyake, Kotaro Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
Ando, Michio Department of Surgery, Anan Kyoei Hospital
Kita, Yoshitaka Department of Surgery, Anan Kyoei Hospital
Hashimoto, Takayo Department of Surgery, Anan Kyoei Hospital
Sannomiya, Kenji Department of Surgery, Anan Kyoei Hospital
Kushida, Toshiaki Department of Surgery, Anan Kyoei Hospital
Sakikawa, Hikari Department of Surgery, Anan Kyoei Hospital
Shimada, Mitsuo Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
We report 2 cases of rectal cancer responding to postoperative chemotherapy with 5-fluorouracil and isovorin. Case 1 : A 60 years-old woman underwent low-anterior resection for rectal cancer in 1994 and partial right lung resection for metastatic lung cancer in 1998. She underwent chemotherapy with 5-fluorouracil and isovorin for mediastinal lymph node metastasis and high score of serum CEA in 2000. After the chemotherapy, the lymph node shrank and serum CEA normalized. Case 2 : A 75 years-old woman underwent low-anterior resection and hysterectomy for rectal cancer with multiple lung metastasis in 2000. She underwent postoperative chemotherapy with 5-fluorouracil and isovorin for metastatic lung cancer. The lung tumor shrank and serum CEA decreased.
Chemotherapy with 5-fluorouracil and isovorin seemed to be effective for advanced colon cancer. We should reconfirm the effectiveness and improve the directions for use.
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