ID 48798
Title Transcription
カンエン カンガン
Title Alternative
Hepatitis and hepatocellular carcinoma
Author
Shimizu, Ichiro Department of Digestive Medicine, Tokushima University Hospital
Ito, Susumu Department of Digestive Medicine, Tokushima University Hospital Tokushima University Educator and Researcher Directory
Keywords
hepatitis C virus
hepatocellular carcinoma
interferon
hepatic fibrosis
oxidative oxidative
Content Type
Journal Article
Description
Hepatitis C virus (HCV) was initially detected in 1989. Therefore, blood transfusion before 1989 may have resulted in infection with HCV. Acute hepatitis related to HCV does not cause any symptom, and is not recognized for a long period. Subsequent chronic hepatitis also causes no symptom. The condition slowly deteriorates, leading to liver cirrhosis after 20 to 30 years. Then, it causes an extremely high incidence of hepatocellular carcinoma (HCC) after 30 to 40 years. To prevent the progression of liver disease with HCV infection, hematology involving the AST/ALT levels, platelet count and specific tumor markers, and abdominal echography, CT and MRI should be periodically performed. Obesity and alcoholism accelerate the progression of liver disease. Treatment with interferon, the only agent that is able to remove HCV from the liver, must be administered. Even when HCV is not removed, the progression at a limited rate may prevent HCC.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
61
Issue
5-6
Start Page
147
End Page
154
Sort Key
147
Published Date
2005-12-20
Remark
EDB ID
FullText File
language
jpn
departments
Medical Sciences