| ID | 50533 |
| Title Transcription | キョウマク チュウヒシュ ノ ソシキ シンダン ニオケル モンダイテン
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| Title Alternative | Diagnotic issues of pleural mesothelioma by immunohistochemical markers
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| Author |
Izumi, Keisuke
Department of Molecular and Environmental Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
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Bando, Yoshimi
Department of Molecular and Environmental Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
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Miyamoto, Yasuo
Department of Molecular and Environmental Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
|
| Keywords | pleural mesothelioma
immunohistochemistry
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| Content Type |
Journal Article
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| Description | This minireview discusses diagnostic issues of mesothelioma by immunohistochemical markers．A large number of immunohistochemical markers for distinction between pleural mesothelioma and pulmonary adenocarcinoma has been reported to date．Ordóñez, N.G. described that calretinin, cytokeratin 5/6 and WT-1 are the best positive markers, and carcinoembryonic antigen （CEA）, MOC-31 and Ber-EP 4 are the best negative markers for mesothelioma, and recommended the selection of two positive and two negative markers．We evaluated the significance of calretinin, cytokeratin 5/6, mesothelin，CEA, MOC-31 and new marker D 2-40 in 19 mesotheliomas and 19 lung adenocarcinomas．We concluded that calretinin, cytokeratin 5/6，D 2-40 and CEA are the most stable immunohistochemical markers for diagnosis of mesothelioma.
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| Journal Title |
四国医学雑誌
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| ISSN | 00373699
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| NCID | AN00102041
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| Publisher | 徳島医学会
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| Volume | 62
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| Issue | 1-2
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| Start Page | 15
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| End Page | 18
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| Sort Key | 15
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| Published Date | 2006-04-25
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| Remark | |
| EDB ID | |
| FullText File | |
| language |
jpn
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| departments |
University Hospital
Medical Sciences
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