ID 83267
Author
Kubo, Shin-ichi Department of Legal Medicine, The University of Tokushima School of Medicine
Ogata, Mamoru Department of Legal Medicine, Faculity of Medicine, Kagoshima University
Kitamura, Osamu Department of Forensic Medicine, The Jikei University School of Medicine
Nakasono, Ichiro Department of Legal medicine, Nagasaki University School of Medicine
Keywords
tetralogy of Fallot
forensic pathology
cause of death
traffic accidental death
immunohistochemistry
Content Type
Journal Article
Description
The case of a61-year-old male traffic accident victem with Tetralogy of Fallot (TOF) is reported. The autopsy revealed massive hemorrhages in the subcutaneous tissue, muscle, and subarachnoidal space. Furthermore, multiple fractures of ribs, sternum and thoracic vertebrae were observed. Histopathological examination revealed changes characteristic of trauma, such as acute lung congestion, acute renal cortical necrosis, and embolization in the lungs and kidney. These autopsy and histological observations indi-cated that traumatic shock was cause of his death. Moreover, histologically, we observed changes due to his congenital heart disease, such as right ventricular hypertrophy, heart failure cells in the lungs, sclerosis of the liver, and hyaline degeneration in the kidney. Furthermore, ischemic changes, shrinkage or loss of neurons, were seen in hippocampus, and swelling of astrocytes in both cortex and hippocampus were also observed. These observations lead us to speculate that a hypoxic episode may have caused his accidental death while driving.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
46
Issue
1-2
Start Page
115
End Page
119
Sort Key
115
Published Date
1999
Remark
FullText File
language
eng