ID 84161
Title Transcription
ダイチョウ センコウ ショウレイ ニ タイスル エンドトキシン キュウチャク リョウホウ ノ ケントウ
Title Alternative
A study on therapeutic results of PMX-DHP for colorectal perforation in our hospital
Author
Kaneda, Yuji Department of Surgery, Tokushima Prefectural Miyoshi Hospital
Yada, Seigo Department of Surgery, Tokushima Prefectural Miyoshi Hospital
Yamaguchi, Takeshi Department of Surgery, Tokushima Prefectural Miyoshi Hospital
Miyauchi, Takayuki Department of Surgery, Tokushima Prefectural Miyoshi Hospital
Kuratate, Masashi Department of Surgery, Tokushima Prefectural Miyoshi Hospital
Yogita, Shiro Department of Surgery, Tokushima Prefectural Miyoshi Hospital
Keywords
PMX-DHP
ARDS
ALI
P/F ratio
perforation of colon
Content Type
Journal Article
Description
The aim of this retrospective study was to investigate the therapeutic results of Polymyxin Bimmobilized Direct Hemoperfusion(PMX-DHP)for colorectal perforation. The study subjects were 40 patients with colorectal perforation surgically treated from 1993 through 2004, of whom 18 underwent PMX-DHP after operation(P group)and 22 underwent operations only(N group). Although there was no significant difference between the two groups in the overall mortality rate, the mortality rate for ARDS was significantly lower in the P group than in the N group. There was a statistically significant correlation between the P/F ratio and the time interval from the disease onset(r=-0.590, p=0.0009<0.001). The time lag from disease onset to operation and the length of PMX-DHP period were significantly longer in the death group than in the survivor group. We anticipate that PMX-DHP for colorectal perforation proves effective in reducing deaths from ARDS. For an effective facilitation of PMX-DHP, the procedure should be started as soon as possible from the onset of the disease.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Volume
63
Issue
1-2
Start Page
40
End Page
43
Sort Key
40
Published Date
2007-04-25
Remark
FullText File
language
jpn