ID 97857
Title Transcription
シン サルコイドーシス シンダン ノ テビキ ニオケル カクシュ シンダン モダリティー ノ ケントウ
Title Alternative
Validation of diagnostic tests for diagnosing cardiac sarcoidosis
Author
Hara, Tomoya Center for Post-graduate Medical Education Hospital, Tokushima University Hospital
Iwase, Takashi Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN Search Researchers
Takashima, Akira Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
Yamasaki, Hiromu Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
Ogasawara, Kozue Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
Bando, Sachiko Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
Ise, Takayuki Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Niki, Toshiyuki Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
楠瀬, 賢也 Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Sumitomo-Ueda, Yuka Center for Post-graduate Medical Education Hospital, Tokushima University Hospital|Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
Tomita, Noriko Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
Yamaguchi, Koji Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Taketani, Yoshio Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN Search Researchers
Yamada, Hirotsugu Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Soeki, Takeshi Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Wakatsuki, Tetsuzo Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Akaike, Masashi Department of Medical Education, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Nose, Hayato Department of Radiology, Institute of Health Biosciences, the University of Tokushima Graduate School
Takao, Shoichiro Department of Radiologic Science and Technology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Otsuka, Hideki Department of Medical Imaging, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Harada, Masashi Department of Radiology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Nishioka, Yasuhiko Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Sata, Masataka Center for Post-graduate Medical Education Hospital, Tokushima University Hospital|Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
cardiac sarcoidosis
cardiac magnetic resonance imaging
late gadolinium enhancement
Content Type
Journal Article
Description
Background : Sarcoidosis is a multiple organ granulomatous disease of undefined cause. Although cardiac involvement often leads to adverse outcomes in patients with sarcoidosis, diagnosis of cardiac sarcoidosis(CS)remains difficult due to the lack of sensitive diagnostic tests.
Purpose : To determine an appropriate combination of diagnostic tests for detecting CS.
Method and Results : Thirteen patients were diagnosed with CS from December 2006 to November2010by the use of2006revised guidelines for diagnosing CS of the Japanese Society of Sarcoidosis and Other Granulomatous Disorders. Positive rate of each major or minor criterion in the guidelines was examined. We also evaluated positive rate of each diagnostic test. In the major criteria, basal thinning of the ventricular septum showed a high positive rate of71.4%, although the others were less than50%. In the minor criteria, positive rates of abnormal electrocardiogram findings and abnormal echocardiogram were76.9% and84.6%, respectively. Late gadolinium enhancement (LGE)of the myocardium on cardiac MRI scanning(CMR)showed a positive rate of100% ; however, CMR was not performed in four patients due to life-threatening arrhythmia. All13patients showed abnormal findings at least in either echocardiogram or LGE on CMR.
Conclusion : Echocardiography is a convenient diagnostic test for detecting CS. The combination of cardiac MRI and echocardiography may improve diagnostic sensitivity.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
67
Issue
5-6
Start Page
253
End Page
256
Sort Key
253
Published Date
2011-12-25
Remark
FullText File
language
jpn
departments
University Hospital
Medical Sciences