ID 97858
Title Transcription
ヒフ ランダム セイケン ガ シンダン ニ ユウヨウ デ アッタ ケッカンナイ リンパシュ ノ イチレイ
Title Alternative
A case of intravascular large B -cell lymphoma diagnosed by random skin biopsy
Author
Fujioka, Keisuke The Post-graduate Education Center, Tokushima University Hospital Tokushima University Educator and Researcher Directory
Saijo, Atsuro Department of Respiratory Medicine and Rheumatology, Tokushima University Hospital Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Toyoda, Yuko Department of Respiratory Medicine and Rheumatology, Tokushima University Hospital Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kakiuchi, Souji Department of Respiratory Medicine and Rheumatology, Tokushima University Hospital KAKEN Search Researchers
Hanibuchi, Masaki Department of Respiratory Medicine and Rheumatology, Tokushima University Hospital KAKEN Search Researchers
Azuma, Masahiko Department of Respiratory Medicine and Rheumatology, Tokushima University Hospital Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Takeuchi, Kyouko Department of Hematology, Tokushima University Hospital
Udaka, Kengo The Post-graduate Education Center, Tokushima University Hospital
Mizutani, Tomoya Department of Dermatology, Tokushima University Hospital
Nishioka, Yasuhiko Department of Respiratory Medicine and Rheumatology, Tokushima University Hospital Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
fever of unknown origin
intravascular large B-cell lymphoma
random skin biopsy
Content Type
Journal Article
Description
A62‐year‐old woman was referred to our hospital for further examination of fever of unknown origin, splenomegaly and pancytopenia. On admission, she had persistent fever and psychological symptoms. Blood examination showed pancytopenia and elevated level of LDH, soluble IL‐2receptor and ferritin. Computed tomography showed multiple low density areas in the spleen, but no systemic lymphadenopathy. In magnetic resonance imaging of the pons, a low and high intensity area on T1‐and T2‐weighted image, respectively, was detected. Taken together these findings, she was suspected to have hepatosplentic T-cell lymphoma or intravascular large B-cell lymphoma. To make a definite diagnosis, random skin biopsy was performed. Immunohistochemical stainings revealed the massive infiltration of CD20‐and CD79α‐positive large lymphoid cells inside the vessels, which yielded the diagnosis of intravascular large B-cell lymphoma.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
67
Issue
5-6
Start Page
257
End Page
262
Sort Key
257
Published Date
2011-12-25
Remark
EDB ID
FullText File
language
jpn
departments
Medical Sciences
University Hospital