ID 98222
Title Transcription
アクセイ キョウマク チュウヒシュ ノ チリョウ : アタラシイ トリクミ オ マジエテ
Title Alternative
Treatment for malignant pleural mesothelioma
Author
Yano, Seiji Department of Internal Medicine and Molecular Therapeutics, Tokushima University Hospital
Keywords
mesothelioma
pemetrexed
molecular targeted therapy
VEGF
orthotopic model
Content Type
Journal Article
Description
Malignant pleural mesothelioma(MPM)arises from the mesothelial cells that line the thoracic cavity.MPM grows aggressively with dissemination in the thoracic cavity and frequently produces malignant pleural effusion.Although a surgical resection at an early stage is the only a curative therapeutic modality, the majority of MPM patients are found at an advanced stage.In addition, MPM is refractory to conventional chemotherapy and radiotherapy, and it also has a poor prognosis.Recently, it has been shown that palliative chemotherapy with pemetrexed and cisplatin is beneficial for MPM patients.Development of novel molecular targeted therapy is essential for further improvement of the prognosis of this disease.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
62
Issue
1-2
Start Page
26
End Page
29
Sort Key
26
Published Date
2006-04-25
Remark
FullText File
language
jpn