ID 113626
Title Alternative
限局性前立腺癌に対するI-125 シード線源永久挿入による排尿障害予測因子
Predictive Factors for Prolonged Urination Disorder After Brachytherapy
Author
Daizumoto, Kei The University of Tokushima
Tsuda, Megumi The University of Tokushima
Keywords
Brachytherapy
Prostate cancer
International Prostate Symptom Score : IPSS
Lower Urinary Tract Symptom : LUTS
Content Type
Thesis or Dissertation
Description
Background: We assessed the change in LUTS after prostate brachytherapy to reveal factors for prolonged urination disorder. Materials and Methods: Four hundred and fourpatients received prostate brachytherapy at our institution and were followed-up for at least 2 years. We evaluated the correlation of mean IPSS changes and clinical factors. Using multivariate analysis, we also evaluated clinical factors with potential to delay IPSS resolution. Results: In cases with prostate volume more than 30 cm3, radiation dose to 90% of prostate volume (D90) more than 160 Gy, and radiation dose to 30% of the urethral volume (UD30) more than 240 Gy, mean IPSS levels were significantly higher, even 30 months after treatment. On multivariate analysis, baseline IPSS more than 8 points and D90 more than 160 Gy were significant predictors for delayed IPSS resolution. Conclusion: Our data suggest that higher baseline IPSS and higher D90 were predictors for prolonged urination disorder.
Journal Title
in vivo
ISSN
0258851X
17917549
NCID
AA10714348
Publisher
International Institute of Anticancer Research
Volume
31
Issue
4
Start Page
755
End Page
761
Published Date
2017-07
Remark
内容要旨・審査要旨・論文本文の公開
本論文は,著者HIDEHISA MORIの学位論文として提出され,学位審査・授与の対象となっている。
P.755著者の英語表記に誤植(誤)YOSHIHITO KUSUHARA(正)YOSHITO KUSUHARA
Rights
Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第3315号
Diploma Number
甲医第1419号
Granted Date
2019-05-23
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
University Hospital
Medical Sciences