Takeda, Tomoya Tokushima University
Nakataki, Masahito Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Ohta, Masashi Tokushima University Tokushima University Educator and Researcher Directory
Hamatani, Sayo Chiba University
Matsuura, Kanae Tokushima University
Yoshida, Reona Tokushima University
Umehara, Hidehiro Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kinoshita, Makoto Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Numata, Shusuke Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Sumitani, Satsuki Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers
defeatist performance belief
negative and positive automatic thoughts
subjective quality of life
objective quality of life
Thesis or Dissertation
Purpose: Recently, cognitive variables such as negative and positive self-belief and thoughts have attracted much attention because they are associated with functional outcomes and quality of life (QOL). However, it is unclear how cognitive variables affect subjective and objective QOL. This study aimed to investigate the relationship of negative and positive self-belief and thoughts with subjective and objective QOL.
Participants and methods: Thirty-six people with schizophrenia participated in this study. Subjective and objective QOL were assessed with the Schizophrenia Quality of Life Scale (SQLS) and Quality of Life Scale (QLS), respectively. Neurocognitive function was assessed with the Brief Assessment of Cognition in Schizophrenia (BACS). Clinical symptoms were assessed with the Positive and Negative Syndrome Scale and Calgary Depression Scale for Schizophrenia. Side effects were assessed with the Drug-induced Extrapyramidal Symptoms Scale (DIEPSS). Negative and positive self-belief and thoughts were assessed with the Defeatist Performance Belief Scale and Automatic Thoughts Questionnaire-Revised. A generalized linear model was tested, with subjective and objective QOL as the response variable and symptoms, neurocognitive function, and cognitive variables that were significantly correlated with subjective and objective QOL as explanatory variables.
Results: In the schizophrenia group, the common objects score on the QLS was predicted by the composite BACS score, and the total QLS score was predicted by the DIEPSS score. Motivation and Energy, Psychosocial, and Symptoms and Side effects scores on the SQLS were predicted by depression and by negative automatic thought (NAT) and positive automatic thought (PAT).
Conclusion: Our results indicated that key targets for improving objective and subjective QOL in people with schizophrenia are side effects, neurocognitive function, depression, and NAT and PAT.
Neuropsychiatric Disease and Treatment
Dove Medical Press
© 2019 Takeda et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/ ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php ).
|DOI (Published Version)|
|URL ( Publisher's Version )|
k3261_abstract_review.pdf 253 KB
k3261_fulltext.pdf 459 KB
|MEXT report number||
Doctor of Medical Science
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