ID | 118536 |
Title Alternative | Sudden death after COVID-19 vaccination
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Author |
Nushida, Hideyuki
Tokushima University
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Kurata, Hiromitsu
Tokushima University|Nakazu-Yagi Hospital
Umemoto, Hitomi
Tokushima University
Iseki, Hirofumi
Tokushima University|Nakazu-Yagi Hospital
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Keywords | Systemic inflammation
Myopericarditis
COVID-19
Vaccines
Sudden death
Autopsy
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Content Type |
Journal Article
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Description | A 14-year-old Japanese girl died unexpectedly 2 days after receiving the third dose of the BNT1262b2 mRNA COVID-19 vaccine. Autopsy findings showed congestive edema of the lungs, T-cell lymphocytic and macrophage infiltration in the lungs, pericardium, and myocardium of the left atria and left ventricle, liver, kidneys, stomach, duodenum, bladder, and diaphragm. Since there was no preceding infection, allergy, or drug toxicity exposure, the patient was diagnosed with post-vaccination pneumonia, myopericarditis, hepatitis, nephritis, gastroenteritis, cystitis, and myositis. Although neither type of inflammation is fatal by itself, arrhythmia is reported to be the most common cause of death in patients with atrial myopericarditis. In the present case, arrhythmia of atrial origin was assumed as the cause of cardiac failure and death. In sudden post-vaccination deaths, aggressive autopsy systemic search and histological examination involving extensive sectioning of the heart, including the atrium, are indispensable.
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Journal Title |
Legal Medicine
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ISSN | 18734162
13446223
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NCID | AA11327981
AA11644485
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Publisher | Elsevier
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Volume | 63
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Start Page | 102244
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Published Date | 2023-03-20
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Rights | © 2023. This manuscript version is made available under the CC-BY-NC-ND 4.0 license
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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DOI (Published Version) | |
URL ( Publisher's Version ) | |
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language |
eng
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TextVersion |
Author
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departments |
Medical Sciences
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