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ID 115514
Author
Sawada, Daisuke Asahi Group Holdings
Tanaka, Hiroki Tokushima University
Hara, Susumu Aoyama Gakuin University
Uchiyama, Yoshihide Aoyama Gakuin University
Sugawara, Tomonori Asahi Group Holdings
Fujiwara, Shigeru Asahi Group Holdings
Keywords
Lactobacillus gasseri CP2305
Top athletes
Fatigue
Stress
Microbiota
Content Type
Journal Article
Description
The heat-inactivated, enteric-colonizing Lactobacillus gasseri CP2305 (CP2305) ameliorates psychological stress-related symptoms. In this study, we examined effects of CP2305 on top athletes experiencing physical and mental stresses. Forty-nine male university Ekiden (long distance relay race) runners daily took the CP2305-containing beverage for 12 weeks during training for and competing in All-Japan university championships. The CP2305 intake significantly facilitated recovery from fatigue and relieved anxiety and depressive mood, compared with placebo intake. The CP2305 intake significantly prevented the training-induced reduction of hemoglobin and facilitated exercise-induced increase in serum growth hormone levels. The CP2305 intake significantly increased the alpha- and beta-diversities of fecal microbiota, and the compositions of Bifidobacterium and Faecalibacterium. Gene expression profiling of peripheral blood leukocytes indicated that CP2305 prevented the stress-induced changes in the expression of genes related to mitochondrial functions. Our results suggest that daily intake of paraprobiotic CP2305 may be beneficial to athletes facing stressful situations.
Journal Title
Journal of Functional Foods
ISSN
17564646
Publisher
Elsevier
Volume
57
Start Page
465
End Page
476
Published Date
2019-04-24
Rights
This is an open access article under the CC BY license
(http://creativecommons.org/licenses/BY/4.0/).
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences