Activating transcription factor 4, an ER stress mediator , is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib

中村, 信元; 三木, 浩和; ,; ,; 日浅, 雅博; ,; ,; 渡邉, 佳一郎; 原田, 武志; 藤井, 志朗; ,; 賀川, 久美子; ,; 松本, 俊夫; 安倍, 正博

doi:10.1007/s12185-013-1367-z

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Use this link to cite this item : https://repo.lib.tokushima-u.ac.jp/105938

ID	105938
Title Alternative	小胞体ストレスメディエーターであるactivating transcription factor 4はボルテゾミブによる骨芽細胞分化に必須であるが、ボルテゾミブによる過剰な小胞体ストレスは骨芽細胞分化を抑制する ER stress and osteoblastogenesis
Author	Nakamura, Shingen University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers Miki, Hirokazu Tokushima University Tokushima University Educator and Researcher Directory KAKEN Search Researchers Kido, Shinsuke University of Tokushima Nakano, Ayako University of Tokushima Hiasa, Masahiro University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers Oda, Asuka University of Tokushima Amou, Hiroe University of Tokushima Watanabe, Keiichiro University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers Harada, Takeshi University of Tokushima Tokushima University Educator and Researcher Directory Fujii, Shiro University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers Takeuchi, Kyoko University of Tokushima Kagawa, Kumiko University of Tokushima KAKEN Search Researchers Ozaki, Shuji Tokushima Prefectural Central Hospital Matsumoto, Toshio University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers Abe, Masahiro University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords	Myeloma ER stress Bortezomib Proteasome inhibitor Activating transcription factor 4 Osteoblastogenesis
Content Type	Thesis or Dissertation
Journal Title	International Journal of Hematology
ISSN	09255710 18653774
NCID	AA10797094
Publisher	The Japanese Society of Hematology\|Springer nature
Volume	98
Issue	1
Start Page	66
End Page	73
Published Date	2013-05-25
Remark	内容要旨・審査要旨・論文要約の公開内容要旨・審査要旨 : LID201311261003.pdf 論文要約 : LID201405221004.pdf 本論文は, 著者Shingen Nakamuraの学位論文として提出され, 学位審査・授与の対象となっている。
EDB ID	284313
DOI (Published Version)	10.1007/s12185-013-1367-z
URL ( Publisher's Version )	https://doi.org/10.1007/s12185-013-1367-z
FullText File	LID201311261003.pdf 179 KB LID201405221004.pdf 71.4 KB
language	jpn
TextVersion	その他
MEXT report number	甲第2651号
Diploma Number	甲医第1177号
Granted Date	2013-09-26
Degree Name	Doctor of Medical Science
Grantor	Tokushima University
departments	Medical Sciences University Hospital Oral Sciences Institute of Advanced Medical Sciences