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ID 114297
Author
Keywords
Meige syndrome
Deep brain stimulation
Globus pallidus internus
Blepharospasm
Craniocervical dystonia
Segmental dystonia
Content Type
Journal Article
Description
Meige syndrome is a type of segmental dystonia that manifests a combination of blepharospasm and oromandibular dystonia and is often associated with other types of craniocervical dystonia. Although the precise pathogenesis of primary Meige syndrome remains to be elucidated, it has been suggested that this movement disorder might be a basal ganglia disorder. Multiple single case reports and open-labeled small case series have shown that globus pallidus internus deep brain stimulation (GPi-DBS) could result in therapeutic benefits in patients with severe Meige syndrome. However, randomized and controlled trials are necessary to accurately assess the safety and therapeutic efficacy of GPi-DBS in treating patients with Meige syndrome. This short commentary introduces the current use of GPi-DBS in the treatment of medically refractory Meige syndrome.
Journal Title
Journal of Neurology & Neurophysiology
ISSN
21559562
Publisher
OMICS International
Volume
7
Issue
6
Start Page
1000405
Published Date
2016-12-26
Rights
© 2016 Morigaki R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License(https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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DOI (Published Version)
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language
eng
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departments
Medical Sciences