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ID 109553
Author
Yamamoto, Nobuaki Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory
Terasawa, Yuka Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN Search Researchers
Satomi, Junichiro Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN Search Researchers
Morigaki, Ryoma Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Fujita, Koji Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Harada, Masafumi Department of Radiology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Izumi, Yuishin Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Nagahiro, Shinji Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kaji, Ryuji Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
ischemic vessel sign
recanalization
3T MRI
CAS
PTA
rtPA
Content Type
Journal Article
Description
Ischemic vessel signs (IVS) can be detected on 3-tesla T2*-weighted magnetic resonance images as a vessel enlargement at the territory of acute ischemia caused by major vessel occlusion or stenosis. Here, we studied changes in IVS before and after recanalization by the administration of intravenous recombinant tissue plasminogen activator (IV rtPA), carotid artery stenting or percutaneous transluminal angioplasty in patients with major vessel occlusion or stenosis. We performed magnetic resonance imaging for all patients treated by IV rtPA at the time of admission, shortly after and 24-72 hours after treatment with IV rtPA. We reviewed the IVS to assess its natural course of IVS by assessing patients who did not recanalize. IVS tended to disappear after recanalization. Conversely, in patients without recanalization, IVS did not disappear shortly after IV rtPA ; rather, it disappeared 24-72 hours after IV rtPA, especially in the presence of complete infarction. Recanalization by IV rtPA or endovascular treatment contributed to improved clinical deficits or the prevention from further progression. IVS can be a parameter of misery perfusion and an important factor to detect the patients who have an indication of treatment for recanalization.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
61
Issue
1-2
Start Page
190
End Page
196
Sort Key
190
Published Date
2014-02
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences
University Hospital