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ID 116179
Author
Nakamura, Tenta Tokushima University
Ara, Tabassum Tokushima University
Oda, Asuka Tokushima University
Sato, Hideo Tokushima University
Keywords
Antioxidant
Biaryl dimer
Natural product
Dihydroisocoumarin
Content Type
Journal Article
Description
A biaryl dimer based on eurotiumide A, a dihydroisocoumarin-type natural product possessing a 1,4-hydroquinone skeleton, was synthesized herein. The radical scavenging activity and cytotoxicity were evaluated. The prepared biaryl dimer and eurotiumide A displayed comparable potent antioxidant activities to those of α-tocopherol and edaravone. However, the biaryl dimer did not show any cytotoxicity against murine colon and human myeloma cells.
Journal Title
Tetrahedron Letters
ISSN
00404039
NCID
AA00861801
AA11539822
Publisher
Elsevier
Volume
74
Start Page
153176
Published Date
2021-05-10
Rights
© 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Author
departments
Pharmaceutical Sciences
University Hospital
Medical Sciences