Total for the last 12 months
number of access : ?
number of downloads : ?
ID 118799
Title Alternative
Early-term birth and hypoglycaemia
Author
Irahara, Makoto Tsurugi Municipal Handa Hospital|Tokushima University|National Center for Child Health and Development KAKEN Search Researchers
Nagai, Takashi Tokushima Prefectural Hospital
Takeuchi, Shunsuke Tsurugi Municipal Handa Hospital
Tayama, Takahiro Tsurugi Municipal Handa Hospital|Tokushima University
Nii, Mari Tsurugi Municipal Handa Hospital
Katayama, Sachiko Tsurugi Municipal Handa Hospital
Kasai, Kana Tsurugi Municipal Handa Hospital
Doi, Naoko Tsurugi Municipal Handa Hospital
Okitsu, Osamu Tsurugi Municipal Handa Hospital
Keywords
early-term birth
hypoglycaemia
large for gestational age
Content Type
Journal Article
Description
Background : The effect of early-term birth on the development of hypoglycaemia in large-for gestational-age (LGA) neonates is yet to be clarified. This study aimed to clarify the association between hypoglycaemia and early-term birth in LGA neonates. Methods : This single-centre retrospective cohort study evaluated LGA neonates born at term at Tsurugi Municipal Handa Hospital, Japan. Blood glucose levels were measured immediately and at 1, 2, and 4 hours after birth. The association between early-term birth and hypoglycaemia was evaluated using logistic regression analysis. The prevalence of severe hypoglycaemia and hypoglycaemia according to its timing of development was analysed using Fisher’s exact test. Results : In total, 295 neonates were included. Among them, 113 neonates (38.3%) were born at early term and 91 infants (30.8%) had hypoglycaemia. Logistic regression analysis showed a significant association between early-term birth and hypoglycaemia (adjusted odds ratio [95% confidence interval] : 2.691 [1.597 to 4.535]). However, there was no significant between-group difference among those with severe hypoglycaemia. Conclusions : Among LGA neonates, early-term birth is positively associated with neonatal hypoglycaemia. This indicates that among LGA neonates, those born at early term require more careful observation for hypoglycaemia than do those born at later term.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
70
Issue
3-4
Start Page
476
End Page
482
Sort Key
476
Published Date
2023-08
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
University Hospital