| ID | 111861 |
| Title Alternative | Electron microscopic studies of Acanthamoeba : 2 Morphological changes of cultured Acanthamoeba due to anti-amoebic agents
|
| Author |
Yano, Masahiko
The University of Tokushima
Shiota, Hiroshi
The University of Tokushima
Tokushima University Educator and Researcher Directory
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Kato, Toshihiko
The University of Tokushima
Mimura, Yasuo
The University of Tokushima
|
| Keywords | Acanthamoeba
electron microscope
fradiomycin
polyhexamethylene biguanide (PHMB)
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| Content Type |
Journal Article
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| Description | Morphological changes of Acanthamoeba in Peptone-Yeast-Glucose medium containing anti-amoebic agents were studied with transmission electron microscope.
In fradiomycin-treated amoeba, decrease of acanthopodia, vacuolar formation in the ectoplasm and cell collapse were observed. In polyhexamethylene biguanide (PHMB)-treated amoeba, rupture of plasma membrane and degeneration of mitochondria were observed at the early stage. These results indicate that PHMB is more effective than fradiomycin for the treatment of Acanthaoeba keratitis. |
| Journal Title |
Shikoku Acta Medica
|
| ISSN | 00373699
|
| NCID | AN00102041
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| Publisher | 徳島医学会
|
| Volume | 52
|
| Issue | 2
|
| Start Page | 33
|
| End Page | 39
|
| Sort Key | 33
|
| Published Date | 1996-04-25
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| FullText File | |
| language |
jpn
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| TextVersion |
Publisher
|
| departments |
Medical Sciences
|
