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ID 114286
Title Alternative
皮膚悪性黒色腫患者の生存率に生検方法が及ぼす影響
Effect of biopsy on survival of melanoma patients
Author
Seike, Takuya The University of Tokushima KAKEN Search Researchers
Okawa, Katsumasa The University of Tokushima
Senzaki, Yuichi The University of Tokushima
Keywords
Melanoma
Prognosis
Survival rate
Content Type
Thesis or Dissertation
Description
Background Cutaneous malignant melanoma has a poor prognosis. The detrimental effect of incisional biopsies on the outcome of malignant melanoma has been debated. The aim of this study was to determine the effect of the presence and type of biopsy on the prognosis of malignant melanoma.
Methods The medical records of 109 malignant melanoma patients treated at Tokushima University Hospital from 1983 to 2007 were reviewed. After excluding 28 cases with stage 0 disease or incomplete data, 81 cases were analyzed in detail with respect to patient sex, age, tumor site, clinical stage at diagnosis, presence of ulceration or lymph node metastasis, and prognosis. The five-year survival and five-year disease-free survival rates of patients who underwent incisional or excisional biopsies were compared with those who did not undergo a biopsy.
Results The male-to-female ratio was 1:1.19. The mean age was 61.3 years (range, 19–93 years). The most common site was a lower extremity, and the most common clinical stage was stage II. No significant differences in clinicopathological features, five-year survival rates, and five-year disease-free survival rates were observed among the three groups.
Conclusions The presence and type of biopsy neither affected the metastatic rate nor the prognosis of malignant melanoma. The use of incisional biopsies is not encouraged because tumor thickness cannot be measured accurately. However, they may be helpful for confirming the diagnosis if an excisional biopsy cannot be performed.
Journal Title
Archives of Plastic Surgery
ISSN
22346163
22346171
Publisher
Korean Society of Plastic and Reconstructive Surgeons
Volume
41
Issue
2
Start Page
122
End Page
125
Published Date
2014-03-12
Remark
内容要旨・審査要旨・論文本文の公開
本論文は,著者Yutaro Yamashitaの学位論文として提出され,学位審査・授与の対象となっている。
Rights
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0/ ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
乙第2110号
Diploma Number
乙医第1758号
Granted Date
2019-12-26
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
University Hospital
Medical Sciences