ID 110864
Author
Matsushita, Shingo Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN Search Researchers
Naito, Takeshi Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Takebayashi, Masaru Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
Sato, Hiroyuki Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
Shiota, Hiroshi Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
PDT
AMD
PCV
subretinal hemorrhage
risk
Content Type
Journal Article
Description
Purpose : To investigate cases with massive subretinal hemorrhage after photodynamic therapy(PDT). Subjects and Methods : We studied four cases(3 men and 1 woman, mean 80.5 yeas old) with massive subretinal hemorrhage after PDT about type of disease, spot size, period to the onset of hemorrhage, visual acuity (VA) before and after PDT. Results : Four cases consisted of one with age-related macula degeneration (AMD) and 3 with polypoidal choroidal vasculopathy (PCV). The average spot size of PDT was 5525_m. Two patients underwent the second PDT about 3 months after the initial PDT. Four periods to the onset of hemorrhage were 22, 27, 137, and 208 days respectively. The latter 2 cases underwent PDT twice, and the periods were the days from the initial PDT. Two patients among four underwent vitrectomy. Average VA before PDT was 0.20, and the final one was 0.02 after PDT. Conclusions : PDT has a risk to cause massive subretinal hemorrhage leading to grave visual disturbance. Especially PDT for PCV seems to have more risk. Therefore we need to inform patients about the risk before PDT, since treating patients with massive subretinal hemorrhage is very difficult.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
55
Issue
3-4
Start Page
231
End Page
235
Sort Key
231
Published Date
2008-08
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences
International Center