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ID 115595
Title Alternative
Erosive Esophagitis in Women With Metabolic Syndrome
Author
Sogabe, Masahiro The University of Tokushima|Kagawa Prefectural Cancer Detection Center Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Yamanoi, Akira Kagawa Prefectural Cancer Detection Center
Content Type
Journal Article
Description
Obesity and metabolic syndrome (MS) are strongly associated with erosive esophagitis (EE). The prevalence of MS and EE, and the distribution of adipose tissue have been known to differ markedly between men and women. Although the prevalence of EE in men with MS is known to be higher in visceral fat type MS (V-type MS) than in subcutaneous fat type MS (S-type MS), the association between EE and the types of MS in women with MS is unclear. This study was a cross-sectional study elucidating the association between EE and the types of MS in women with MS.
Subjects were 454 women with MS who underwent a regular health check-up. A distinction was made between V-type MS and S-type MS and the prevalence of EE and the association between EE and other data were elucidated.
Although there were some significant different factors in characteristics between V-type MS and S-type MS, there was no significant difference in the prevalence of EE between V-type MS and S-type MS. The presence of Helicobacter pylori (H. pylori) was significantly lower than in subjects with EE (13.7%) than in subjects without EE (41.9%). The frequency of hiatal hernia was significantly higher in subjects with EE (60.8%) than in subjects without EE (24.6%). Logistic regression analysis showed hiatal hernia (odds ratio: 4.673; 95% confidence interval: 2.448–8.920; P < 0.001), hemoglobin A1c (HbA1c) (2.325; 1.110–4.870; P < 0.05), and the presence of H. pylori (0.239; 0.101–0.567; P < 0.005) were significant predictors of the prevalence of EE.
V-type MS may not be such an important factor for the prevalence of EE in women with MS as in men with MS. The absence of H. pylori, hiatal hernia, and HbA1c may be more important for the prevalence of EE than the types of MS in women with MS.
Journal Title
Medicine
ISSN
00257974
15365964
NCID
AA00728867
Publisher
Wolters Kluwer Health
Volume
93
Issue
28
Start Page
e276
Published Date
2014-12
Rights
This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0(https://creativecommons.org/licenses/by-nc-nd/4.0/), where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially.
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language
eng
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departments
Medical Sciences