ID 50533
Title Transcription
キョウマク チュウヒシュ ノ ソシキ シンダン ニオケル モンダイテン
Title Alternative
Diagnotic issues of pleural mesothelioma by immunohistochemical markers
Author
Izumi, Keisuke Department of Molecular and Environmental Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Bando, Yoshimi Department of Molecular and Environmental Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Miyamoto, Yasuo Department of Molecular and Environmental Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
Keywords
pleural mesothelioma
immunohistochemistry
Content Type
Journal Article
Description
This minireview discusses diagnostic issues of mesothelioma by immunohistochemical markers.A large number of immunohistochemical markers for distinction between pleural mesothelioma and pulmonary adenocarcinoma has been reported to date.Ordóñez, N.G. described that calretinin, cytokeratin 5/6 and WT-1 are the best positive markers, and carcinoembryonic antigen (CEA), MOC-31 and Ber-EP 4 are the best negative markers for mesothelioma, and recommended the selection of two positive and two negative markers.We evaluated the significance of calretinin, cytokeratin 5/6, mesothelin,CEA, MOC-31 and new marker D 2-40 in 19 mesotheliomas and 19 lung adenocarcinomas.We concluded that calretinin, cytokeratin 5/6,D 2-40 and CEA are the most stable immunohistochemical markers for diagnosis of mesothelioma.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
62
Issue
1-2
Start Page
15
End Page
18
Sort Key
15
Published Date
2006-04-25
Remark
EDB ID
FullText File
language
jpn
departments
University Hospital
Medical Sciences