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ID 114301
Title Alternative
Left Side Electrode of DBS Caused an Acute Mood Swing
Author
Keywords
Subthalamic nucleus deep brain stimulation
Parkinson’s disease
Manic episode
Depressive episode
Lateral balance
Content Type
Journal Article
Description
No previous reports have described a case in which deep brain stimulation elicited an acute mood swing from a depressive to manic state simply by switching one side of the bilateral deep brain stimulation electrode on and off. The patient was a 68-year-old woman with a 10-year history of Parkinson’s disease. She underwent bilateral subthalamic deep brain stimulation surgery. After undergoing surgery, the patient exhibited hyperthymia. She was scheduled for admission. On the first day of admission, it was clear that resting tremors in the right limbs had relapsed and her hyperthymia had reverted to depression. It was discovered that the left-side electrode of the deep brain stimulation device was found to be accidentally turned off. As soon as the electrode was turned on, motor impairment improved and her mood switched from depression to mania. The authors speculate that the lateral balance of stimulation plays an important role in mood regulation. The current report provides an intriguing insight into possible mechanisms of mood swing in mood disorders.
Journal Title
Clinical Psychopharmacology and Neuroscience
ISSN
17381088
20934327
NCID
AA12041419
Publisher
The Korean College of Neuropsychopharmacology
Volume
16
Issue
4
Start Page
494
End Page
496
Published Date
2018-11-30
Rights
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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language
eng
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departments
University Hospital
Medical Sciences
Academic Support Office for Students with Special Needs