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ID 114355
Title Alternative
INCREASED EXPRESSION OF c-myc GENE
Author
Hirohashi, Setsuo National Cancer Center Research Institute
Sekiya, Takao National Cancer Center Research Institute
Keywords
c-myc
Lung cancer
Colon cancer
Increased expression
Run-on transcription
Content Type
Journal Article
Description
High levels of c-myc mRNA were observed in two human tumor cell lines, a giant cell carcinoma of the lung (C-Lu99) and a colon cancer (C1). The increased expression of c-myc in these cell lines, which was comparable with those in cell lines in which the c-myc gene is amplified, was not due to gene amplification. Run-on transcription revealed that the transcriptional rate of the c-myc gene was greatly increased in these cell lines.
Journal Title
Japanese Journal of Cancer Research
ISSN
09105050
NCID
AA00690844
Publisher
Japanese Cancer Association
Volume
77
Issue
6
Start Page
540
End Page
545
Published Date
1986-06
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Oral Sciences