| ID | 114357 |
| Title Alternative | REARRANGEMENT OF c-myc GENE
|
| Author |
Yoshimoto, Katsuhiko
National Cancer Center Research Institute
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Shiraishi, Masahiko
National Cancer Center Research Institute
Hirohashi, Setsuo
National Cancer Center Research Institute
Morinaga, Shojiroh
National Cancer Center Research Institute
Shimosato, Yukio
National Cancer Center Research Institute
Sugimura, Takashi
National Cancer Center Research Institute
Sekiya, Takao
National Cancer Center Research Institute
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| Keywords | c-myc
Rearrangement of gene
Giant cell carcinoma of the lung
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| Content Type |
Journal Article
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| Description | The c-myc oncogene was found to be rearranged in a human cell line of giant cell carcinoma of the lung (C-Lu65) and in a human primary giant cell carcinoma of the lung (LuC38C). The rearrangements in C-Lu65 and LuC38C were in regions about 7.5kb and 6kb, respectively, upstream from the transcription initiation site. No rearrangement of the c-myc gene was observed in a non-cancerous portion (LuC38N) of the lung of the patient who carried LuC38C. These results suggest that rearrangement of the c-myc gene may play some role in tumorigenesis of giant cell carcinoma of the lung.
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| Journal Title |
Japanese Journal of Cancer Research
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| ISSN | 09105050
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| NCID | AA00690844
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| Publisher | Japanese Cancer Association
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| Volume | 77
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| Issue | 8
|
| Start Page | 731
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| End Page | 735
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| Published Date | 1986-08
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| EDB ID | |
| DOI (Published Version) | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
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| TextVersion |
Publisher
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| departments |
Oral Sciences
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