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ID 113267
Title Alternative
亜急性期脳卒中患者および健常者における歩行観察時のミラーニューロンシステムの活性化
Author
Hioka, Akemi Tokushima University|Tokushima Bunri University
Kitazato, Keiko Tokushima University
Korai, Masaaki Tokushima University
Akazawa, Naoki Tokushima Bunri University
Keywords
gait observation
mirror neuron system
stroke
fMRI
Content Type
Thesis or Dissertation
Description
The observation of walking improves gait ability in chronic stroke survivors. It has also been suggested that activation of the mirror neuron system contributes to this effect. However, activation of the mirror neuron system during gait observation has not yet been assessed in sub-acute stroke patients. The objective of this study was to clarify the activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons. In this study, we sequentially enrolled five sub-acute stroke patients who had undergone gait training and nine healthy persons. We used fMRI to detect neuronal activation during gait observation. During the observation period in the stroke group, neural activity in the left inferior parietal lobule, right and left inferior frontal gyrus was significantly higher than during the rest period. In the healthy group, neural activity in the left inferior parietal lobule, left inferior frontal gyrus, left middle frontal gyrus, left superior temporal lobule and right and left middle temporal gyrus was significantly higher than during the rest period. The results indicate that the mirror neuron system was activated during gait observation in sub-acute stroke patients who had undergone gait training and also in healthy persons. Our findings suggest that gait observation treatment may provide a promising therapeutic strategy in sub-acute stroke patients who have experienced gait training.
Journal Title
Journal of Clinical Neuroscience
ISSN
09675868
NCID
AA10958444
Publisher
Elsevier
Volume
60
Start Page
79
End Page
83
Published Date
2018-10-11
Remark
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Akemi Hiokaの学位論文として提出され, 学位審査・授与の対象となっている。
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第3249号
Diploma Number
甲医第1398号
Granted Date
2019-01-24
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
Medical Sciences
University Hospital