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ID 115756
Author
Suga, Hokuto Kagoshima University
Mishima, Katsuaki Yamaguchi University
Nakano, Hiroyuki Osaka Medical College
Ueyama, Yoshiya Yamaguchi University
Yamasaki, Youichi Kagoshima University
Keywords
Airway obstruction
computational fluid dynamics
computed tomography
obstructive
oral appliance
polysomnography
respiration
sleep apnea
Content Type
Journal Article
Description
Objective: To evaluate the effect of oral appliance (OA) treatment on upper-airway ventilation conditions in patients with obstructive sleep apnea (OSA) using computational fluid dynamics (CFD).
Methods: Fifteen patients received OA treatment and underwent polysomnography (PSG) and computed tomography (CT). CT data were used to reconstruct three-dimensional models of nasal and pharyngeal airways. Airflow velocity and airway pressure measurements at inspiration were simulated using CFD.
Results: The apnea–hypopnea index (AHI) improved from 23.1 to 10.1 events/h after OA treatment. On CFD analysis, airflow velocity decreased at the retropalatal and epiglottis-tip levels, while airway pressure decreased at the retropalatal, uvular- and epiglottis-tip levels. The AHI of patients with OSA before OA treatment was correlated with airway pressure at the epiglottis-tip level.
Discussion: Treatment with OA improved the ventilation conditions of the pharyngeal airway and AHI. Results of CFD analysis of airway pressure and airflow velocity helped determine the severity and ventilatory impairment site of OSA, respectively.
Journal Title
CRANIO: The Journal of Craniomandibular & Sleep Practice
ISSN
08869634
21510903
NCID
AA10783872
Publisher
Taylor & Francis
Volume
39
Issue
3
Start Page
209
End Page
217
Published Date
2019-03-31
Rights
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Oral Sciences